Ana and Alberto get married. Their best friends warn them about the seven year itch: the usual time when a couple starts experiencing big problems in their relationship. We will follow Ana and Alberto on their marriage until they reach their seven year itch.
The Griswalds win a vacation to Europe on a game show, and so pack their bags for the continent. They do their best to catch the flavor of Europe, but they just don't know how to be be good tourists. Besides, they have trouble taking holidays in countries where they CAN speak the language.
In New York City, Thom is broke and jobless, illegally working as a taxi driver. Claire is a successful business-woman, but personally she's in shambles - then comes the phone call that her estranged father is in the hospital. Not knowing what to do, Claire hops in Thom's cab and orders him to just drive and so he does. They find themselves in Pennsylvania and Claire makes the rash decision to drive across the country to California. On the road, there are many detours as the obstacles and secrets force them to learn about themselves and each other.
Twenty-eight-year-old Margot is happily married to Lou, a good-natured cookbook author. But when Margot meets Daniel, a handsome artist who lives across the street, their mutual attraction is undeniable.
Set in Genoa, the film concerns the financial struggles and emotional strain that occur after Michele loses his job. He and his wife Elsa are forced to give up their affluent lifestyle and cope with the tensions of moving into a smaller home, finding new work, and making sacrifices.
Ed and Alice are two months shy of getting married when she realizes that she wishes she'd had a more active love life while still single. Reluctantly, Ed agrees to have an open relationship in the months before their wedding, and initially this seems to improve their connection, particularly in the bedroom. However, as Ed and Alice get more involved in their own flings, the experiment goes awry.
Victoria, Zenobia, Cleavon, and Phil are all friends approaching the age of 35 and struggling to build the families they've always dreamed of. While Zenobia is still looking for a man, Victoria is married to a man who doesn't want children. Cleavon, meanwhile, is too geeky to get a woman, and Phil is already married with children, but his wife is not very interested in being a mother. All four of them try to rectify their romantic lives and futures while their biological clocks tick away.
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