Having lost their status and credibility five years after covering New York City with gooey roasted marshmallows in Ghostbusters (1984), the city's former heroes and once-popular spirit-hunters struggle to keep afloat, forced to work odd jobs. However, when Dana and her baby have yet another terrifying encounter with the paranormal, it is up to Peter Venkman and his fearless team of supernatural crime fighters to step up and save the day. Once more, humankind is in danger, as rivers of slimy psycho-reactive ectoplasm, paired with the dreadful manifestation of evil sixteenth-century tyrant Vigo the Carpathian, threaten to plunge the entire city into darkness. Is the world ready to believe? Can the Ghostbusters save us for the second time?
After losing their academic posts at a prestigious university, a team of parapsychologists goes into business as proton-pack-toting "ghostbusters" who exterminate ghouls, hobgoblins and supernatural pests of all stripes. An ad campaign pays off when a knockout cellist hires the squad to purge her swanky digs of demons that appear to be living in her refrigerator.
While on a dangerous mission to recover the historic Judas Chalice, Flynn is saved by Simone. But when double-crossed by a respected professor and ambushed by a ruthless gang, Flynn realizes Simone's secret, his true mission and a shocking discovery are all lying within a decaying New Orleans crypt.
Following the sudden death of his mother, a mild-mannered but anxiety-ridden man confronts his darkest fears as he embarks on an epic, Kafkaesque odyssey back home.
Sylvia Stickles runs a convenience store with her husband and mother-in-law. One day, Sylvia is hit on the head and transforms from an uptight prude to a sex-crazed lunatic. As she goes on a rampage through town, Sylvia attracts the attention of Ray Ray, a sexual healer and tow truck driver in search of the world's greatest orgasm. Their sexual revolution, however, causes a class war in their tiny Baltimore community.
Young history buff Kevin can scarcely believe it when six dwarfs emerge from his closet one night. Former employees of the Supreme Being, they've purloined a map charting all of the holes in the fabric of time and are using it to steal treasures from different historical eras. Taking Kevin with them, they variously drop in on Napoleon, Robin Hood and King Agamemnon before the Supreme Being catches up with them.
King Arthur, accompanied by his squire, recruits his Knights of the Round Table, including Sir Bedevere the Wise, Sir Lancelot the Brave, Sir Robin the Not-Quite-So-Brave-As-Sir-Lancelot and Sir Galahad the Pure. On the way, Arthur battles the Black Knight who, despite having had all his limbs chopped off, insists he can still fight. They reach Camelot, but Arthur decides not to enter, as "it is a silly place".
An abortion clinic worker with a special heritage is called upon to save the existence of humanity from being negated by two renegade angels trying to exploit a loophole and reenter Heaven.