The 8-year-old Louie is doing his best to grow up and cope with a large family, a doting mother, a pesky little brother, and a by-the-book, military veteran dad. Add to that a slew of holiday family squabbles, a flood, an old Rambler and a huge goldfish, and you have the background for Life with Louie. Each episode is a portrait of humor and warmth drawn from Louie Anderson's real-life experience as a child in the Midwest.
For his vacation science homework, Louie has to give a detailed report on honey bees. He ends up enlisting the help of his father on this project, but Andy ends up taking over the care and observation of the bees and develops a special kinship with the bees. Louie tries to figure out how he is going to give a presentation on the bees when he can't get anywhere near them with his father in the picture.