Shaun Murphy, a young surgeon with autism and savant syndrome, relocates from a quiet country life to join a prestigious hospital's surgical unit. Unable to personally connect with those around him, Shaun uses his extraordinary medical gifts to save lives and challenge the skepticism of his colleagues.
A terminal cancer patient is determined to live the last few months of his life without inhibition; Dr. Reznik must confront her relationship with her mother when she comes in for a third opinion from Dr. Glassman.
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