Four egocentric friends run a neighborhood Irish pub in Philadelphia and try to find their way through the adult world of work and relationships. Unfortunately, their warped views and precarious judgments often lead them to trouble, creating a myriad of uncomfortable situations that usually only get worse before they get better.
When an experiment successfully multiplies Charlie's intellect and takes him away from the bar, the rest of the gang find themselves struggling to complete the menial "Charlie Work" that has kept the bar running for so long.