Set in Springfield, the average American town, the show focuses on the antics and everyday adventures of the Simpson family; Homer, Marge, Bart, Lisa and Maggie, as well as a virtual cast of thousands. Since the beginning, the series has been a pop culture icon, attracting hundreds of celebrities to guest star. The show has also made name for itself in its fearless satirical take on politics, media and American life in general.
Homer's rush to the hospital to reattach his thumb, Lisa's rush to school to win the science fair, and Bart's run-in with an illegal fireworks scheme are interconnected in a parody of Go and Run Lola Run.