The story of New Jersey-based Italian-American mobster Tony Soprano and the difficulties he faces as he tries to balance the conflicting requirements of his home life and the criminal organization he heads. Those difficulties are often highlighted through his ongoing professional relationship with psychiatrist Jennifer Melfi. The show features Tony's family members and Mafia associates in prominent roles and story arcs, most notably his wife Carmela and his cousin and protégé Christopher Moltisanti.
Anatomy of the Mob continues with the rest of the 45 minute interview between Alec and David. This focuses more on talking about casting decisions, the continuing development of the characters throughout the series, why certain ends were met for certain characters and how it affected the people behind the scenes, the stigma of using so many people from famous mob films, and more.